Second NIC wont ping!

I have 2 NICs on the server I’ve installed on, After configuring the second NIC I ping it and it times out. Configuration is good as far as I know. The first NIC is functional. They are set to different subnets with a router acting as a bridge. I can ping the first NIC no problem.

What am I missing?

need a little more info on how you configured NIC 2