Noob question regarding software updates

I have been trying to understand if installing updates outside of the FreePBX Module Admin is recommended (or required even). I installed FreePBX 2.5 + Asterisk 1.4 via AsteriskNow, and have updated to 2.6.0.1.

I also installed Webmin to help with server admin, and I have several modules (both core CentOS modules and Asterisk 1.4) that WebMin says have pending updates, and my question is simple:

Is it OK to install all of the recomended package updates identified outside of the FrePBX admin interface?

Thanks to all for your support, I am new to Asterisk but lots of great info avaialble.

Chris

Non Asterisk/FreePBX modules, I would update through Webmin, Asterisk/FreePBX udpate through the FreePBX setup/update module