I am looking to put together my first freePBX system with a NUC as the server. I will be using 3 POTS lines and was wondering what would work best for integrating them? Was considering the Grandstream 4104.
The Sangoma Vega 50 is what I would recommend. 
I have installed several Grandstreams GXW4104 in case you choose to go that route and need help configuring it.
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I’ve used Synway FXO cards with some reasonable success - they do require more integration than the Sangoma cards, but are rock solid once you get the right DAHDI software installed.
I might have to take you up on that.
Just let me know and I will try to help