Facing error when i click on apply config in free pbx. Need support

exit: 1
Unable to connect to remote asterisk (does /var/run/asterisk/asterisk.ctl exist?)
Exception: Unable to connect to Asterisk through the CLI in file /var/lib/asterisk/bin/retrieve_conf on line 43
Stack trace:

  1. Exception->() /var/lib/asterisk/bin/retrieve_conf:43