408 timeout for remote pjsip extensions

Hello guys, I’m trying to determine what can be the reason for the 408 timeout that we see for external Softphone clients. When it happens, the messages are not reaching asterisk. Usually we fix it by restarting the sangoma firewall and fail2ban or restart asterisk (which causes firewall to be reloaded). Responsive firewall is enabled. FreePBX distro is SNG7.
Any sugegstions?

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